Hereditary angioedema (HAE) in summary
What is HAE?
HAE is a rare and life-long, genetic condition that affects somewhere between 1 in 10,000–50,000 people.1–5 It is usually caused by your body not producing enough of, or not properly producing, a blood protein called C1 inhibitor.1–5 This leads to your body producing too much of another protein called bradykinin, which can cause an HAE attack.1–5
What happens during an HAE attack?
During an attack, fluid in the blood vessels begins to leak out into the surrounding area, causing painful and sometimes disfiguring swelling.1,2,5 It most commonly affects the face, feet, hands, stomach, genitals, and sometimes the throat.1–6 Attacks on the throat happen less often but they can be life-threatening, as swelling here can interfere with your breathing.2–4 If you experience an HAE attack affecting your airways, inject SAJAZIR (icatibant) and then go to the nearest hospital emergency room right away.6
How is HAE diagnosed?
Exactly where in the body, how often and how severe is different for everyone and can change over time.1 Because HAE is so rare, it can be difficult to diagnose in the beginning and symptoms are often confused with other conditions, such as allergies.5
If you’ve been diagnosed with HAE and are receiving SAJAZIR treatment, Cycle Vita is here for you, for life.
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References
- Maurer M, et al. Allergy. 2018;73(8):1575–1596.
- Zuraw BL, et al. J Allergy Clin Immunol Pract. 2013;1(5):458–467.
- El-Shanawany T. Hereditary Angioedema. British Society for Immunology. https://www.immunology.org/public-information/bitesized-immunology/immune-dysfunction/hereditary-angioedema (accessed October 2021).
- Ghazi A, Grant JA. Biologics. 2013;7:103–113.
- Lumry W, et al. Journal of Infusion Nursing. 2020;43(3):134–145.
- SAJAZIR™ (icatibant) Injection. Prescribing Information. Cycle Pharmaceuticals Limited.